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It is likely that defective HR in BRCA1/2-mutant tumour cells also underlies their hypersensitivity to IR and DNA crosslinking agents, which may ultimately impact on the chances of combination cancer therapy to achieve tumour eradication.
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The ICC had, of necessity, to recruit widely to hire the 57,000 people it needed and this, it noted, had one beneficial result: the many different races and nationalities minimised the chances of "the combination" of the workforce "which would be disastrous .The chastened political left sought solace in the thought that the Panama and Erie canals were fine advertisements for state enterprise.
In tic disorders (TD), co-existence with ADHD can be found in about 50% of patients, while in ADHD patients a TD is seen in about 20%: Both figures are above the chance rate of combination [ 121].
* It could foreclose any chance of a combination with any other search provider that is not already relying on Google's search services.
When it comes to assessing the chances of some complicated combination of events, gut feelings are pretty much useless.
They're separately really rare – PNH is one in a million – and the chances of getting a combination of them is unbelievably small.
I had never eaten anything quite like it, and my chances of creating this combination in my kitchen are about the same as that monkey typing Shakespeare.
We kept the ball well, created chances, played a lot of combination play and dictated the flow of the game.
As heavy chain amplification was biased towards the expression of a set of heavy chain genes, to avoid predominant expression of one subset of genes in the phage library, we took an equal concentration of all the heavy chain genes which in turn increased the chances of the new combinations that are not expressed in natural infection.
But York also had their chances, a combination of sloppy passing in the final third, a reluctance to shoot and some last-ditch defending ensuring that it stayed 0-0.
Chances are combination of sorafenib and 5-FU would exert a synergetic effect with the hypothesis that sorafenib could reverse the resistance to 5-FU of HCC cells by inhibiting p-ERK expressions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com