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However, increased testing also increases the chance of false error reports, and in our experience this brings with it a danger of developing complacency on the part of the tester ('I've seen that fail before, I won't worry about that').
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To minimize the chance of false positives due to sequencing errors, the minimum variant frequency was set to 35%, and only sites with more than 10X coverage were included for SNP detection.
It has also been shown that in the case of logistic regression the chance of false positives is increased; as the sample size increases, so does the chance of such errors (Austin and Brunner, 2004).
This result provides a more confident answer with less chance of false positive and false negative outcomes.
Therefore, we may detect the bot program's existence with a low chance of false alarms.
Too many "red flags" would increase the chance of false alarms and would themselves be increasingly costly to analyze.
However, the chance of false positive result as described by the false discovery rate was low.
Therefore, we examined for possible imputation errors by comparing with de novo genotyping in a random sample of the RS-I and the Twins UK studies to exclude any chance of false positive findings.
There is a small chance of false positives, which would bias our estimates upwards.
We limited the chance of false positive results by applying a two-step strategy.
In our study, we used cross-validation methods to significantly reduce the chance of false positives.
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