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The large number of GO categories increases the chance of alignment with the unknown disease biology underlying the GWAS results and the smaller number of results provided by the KEGG analysis supports this conclusion.
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E-value, minimum e-value (probability of alignment occurring by chance) recorded for a hit.
Although this increases the chance of incorrect alignment, it increases the total number of aligned reads and may facilitate the discovery of novel transcription events, which can subsequently be validated.
Only reads with a mapping quality (MQ) score ≥20, or a 99% chance of correct alignment, were included for further analysis.
In the spirit of creative fragmentation, why not take advantage of the chance alignment of unrelated recordings to traverse the "Ring" (three-fourths of it, anyway) in contrasting readings, all live, all unfamiliar?
And all too often, classes can be packed, with students having no chance of their poor alignment being corrected.
Some conformers may have different optimal alignments with a reference shape due to structural symmetry; however, the presence of multiple reference shapes greatly increases the chance of finding an alignment very close to the analytical maximum overlap solution.
For this reason, Proxima is sometimes referred to as Alpha Centauri C. Modern estimates, taking into account the small separation between and relative velocity of the stars, suggest that the chance of the observed alignment being a coincidence is roughly one in a million.
The latter was introduced as a conservative approach to limit the fraction of spurious hits that could result from chance alignments of reads of exogenous origin to the horse genome.
Many startups are a product of chance alignment in time, space and inspiration.
Taking advantage of a rare chance alignment of eight Earth-orbiting spacecraft, space physicists have pinned down where and how the energy of the solar wind can surge Earthward to power the celestial light of the auroras and help fire up the Van Allen radiation belts.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com