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However, rather than merely calculate the percentage of cases on which they agree, the Kappa statistic corrects for "chance" agreement, where "chance" is a function of the prevalence of the condition being assessed.
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Consider the probability that a read maps at exactly one position in the genome by chance, that is a function of the number of mapping positions (approximately the length of the genome, L, multiplied by the number of colors) and the number of potential different sequences (4 l, where l is the read length).
Strongly interacting pairs have an even larger chance of being detected, as the probability of passing the filtering stage is a function of the GLR score.
Boredom is a function of attention.
"Diabetes is a function of development.
"But longevity is a function of performance".
Happiness is a function of fulfilment.
That is a function of the market.
Maybe that is a function of television.
"Oil is a function of global growth.
Hope is a function of struggle.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com