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An acidic environment would have further increased the stability of RNA and therefore the chances for its evolution.
Likewise, acidic pH would have enhanced the half-life of the aminoacyl- t RNA bond, increaminoacyl- t RNAs for the evolution of protein synthesis.
This type of scenario would thus involve two or more steps like the Dobzhansky-Muller model, but the fundamental difference with the Dobzhansky-Muller model is that selective pressures would be driving the isolation, rather than rely on chance for the separate evolution of two traits that will, at a later stage, turn out to be incompatible.
Simultaneous use of phages and antibiotics may help to minimize the chance of resistance evolution for the same reasons as treatment with multiple antibiotics (Bonhoeffer et al. 1997; Lipsitch and Levin 1997; Chow and Yu 1999; Yeh et al. 2009; zur Wiesch et al. 2011).
Aikin and Casey [2011] Overemphasizing aspects of "chance" in evolution.
These associations did not occur by chance during evolution.
The reason was that a single mutation would then possibly alter two different proteins, greatly reducing the chance of a beneficial change happening for evolution.
Voices for evolution.
Which leaves plenty of room for evolution.
Yes, the evidence for evolution is irrefutable.
That variation is the grist for evolution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com