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UPF1 silencing led to the up-regulation of 1251 genes in HCT116, among which a proportion of them (i.e. 38%) significantly higher than expected by chance contained a coding microsatellite (P<2×10−16).
In this study, we also investigate large scale gene expression changes in MSI CRC cells in the context of NMD inhibition using a specific method, showing that it led to the up-regulation of 1251 genes in HCT116, among which a proportion of them significantly higher than expected by chance contained a coding microsatellite.
The test set by chance contained 84% of the positive thio-containing chemicals.
The fragment lengths from single clone analyses that by chance contained cDNAs from the same gene reproduced very accurately.
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Clearly a random choice of negatives can introduce bias into the classifier since it could by chance contain unknown, but real, target genes even if the average number of expected targets is negligible.
There's a good chance it contains uranium!
If you backed down from the use of force, you reduced the chance of containing Saddam.
Its purpose: Identify disease outbreaks early, while there is still a chance to contain them.
If they fail, the chance to contain North Korea's nuclear ambitions could be lost.
Gordon Brown, the chancellor, is now the last chance to contain Auntie.
Firm judges, unintimidated by loose congressional threats, offer the best chance to contain them.
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