Sentence examples for challenging with many from inspiring English sources

This was challenging with many students in each PE class.

Identifying exact causative genes has been challenging, with many discoveries not replicated.

Communicating effectively and appropriately across language, religious or cultural difference can be challenging with many possibilities for misunderstanding, perceived offence and disempowerment.

Empirical treatment for nosocomial UTI or infection with multi-drug resistant isolates remains challenging with many authorities recommending parenteral carbapenems (imipenem, ertapenem or meropenem) [ 11] especially where ESBL producing isolates may be involved.

The IMF's researchers stressed that the prospect of losses on central banks' balance sheets should not prevent them from unwinding their unconventional policies, but warned that, "the path ahead will be challenging, with many unknowns".

Production of fuel ethanol from lignocellulosic biomass remains challenging, with many opportunities for improvement.

The one (considerable) drawback is that the road off the A87 to Glenelg is narrow, banked and not for the vertiginously challenged, with many steep switchbacks.

These interesting presentations challenge us with many new questions regarding optimal adjuvant hormonal therapy.

Treatment of chronic wounds can present a challenge, with many patients remaining refractory to available advanced therapies.

A scale-up of controlled-release processing can be a daunting challenge with many factors potentially affecting the overall outcome.

Implementation and financing this policy has been a challenge with many recommendations for improvement and successful implementation and is a topic that is being refined in international dialoges.