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We demonstrate this new reactivity through a highly enantioselective radical dehalogenation of lactones a challenging transformation for small-molecule catalysts4,5,6,7.
Using the new reactivity of the ketoreductase, the authors carry out enantioselective dehalogenation of lactones by irradiation with visible light, a challenging transformation by traditional small-molecule catalysis.
To I.S.S., the only real alternative to the leveraged buyout was leaving Dell alone, in that way having shareholders bear the risks of supporting a challenging transformation.
This became the starting shot for the company's radical and sometimes challenging transformation from a local Chinese to a truly global corporation.
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And instead of challenging this transformation, as they are supposed to – certainly at the more thoughtful edges of the art – novelists are buying into it wholesale.
Although metabolic technologies have been applied to find biomarkers for a few cancerous and virally transformed cell types [9], [12], [13], [14], [15], these techniques need to be expanded for challenging viral transformations, such as human immunodeficiency virus (HIV) and HTLV1.
We believe that the present system should contribute to the realization of challenging molecular transformations by making use of the high reactivity of NHC-based FLPs.
To manage these momentous challenges, transformations, threats and opportunities, utilities need managers who are able to work simultaneously with large, sophisticated organizations but also able to communicate with small departments with a start-up culture.
In another potentially rich, though challenging avenue for transformation, cloud configurations are ocassionaly suggested by broad diagonal lines.
A particular challenging class of transformations in this respect are the widely used transition metal-catalysed reactions.
The work of transformation is challenging stuff, and so is the task of envisioning a truly transformed future.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com