Sentence examples for challenging to sequence from inspiring English sources
He also had problems moving, struggled to recognise everyday objects, and found it challenging to sequence everyday tasks.
The only missed disease-causing mutation was located in a homopolymer stretch, regions that are challenging to sequence with Ion Torrent technology [ 42– 42].
Plant species, many of which have large complex genomes with a history of ancient and recent duplications are still challenging to sequence.
In addition, we evaluated the performance of an augmented exome strategy, ACE, that extends coverage in medically relevant regions and enhances coverage in areas that are challenging to sequence.
Prof Robert Martienssen, from the Cold Spring Harbour Laboratory in the US, said: "These large plant genomes are very challenging to sequence, in part because of the size, but also because they have a lot of repetitive sequences, which makes it difficult to put the jigsaw puzzle together.
Assessing the extent to which a spidroin is homogenized within a single gene or among individuals is difficult because the repetitive region makes it exceptionally challenging to sequence complete spidroin genes.
L. hesperus has an estimated genome size of 1.3 billion bp [ 42], which while on the lower range of spider genomes, would be challenging to fully sequence.
Repetitive sequences are technically challenging to clone and sequence and can be better studied by combining various approaches like mapping and sequence analysis.
It is well established that FFPE tumour DNA samples are challenging to amplify and sequence due to damage resulting from the fixation process and due to sample heterogeneity.
However, even when RenSeq data was used to map the resistance to specific loci, it is still challenging to define the sequence of each paralogue in a multigene family.
AS WE report in this week's print edition, the X Prize Foundation has just announced a new challenge: to sequence the genomes of 100 centenarians in 30 days for less than $1,000 each.
