Alopecia areata (AA) is a common autoimmune disease and it is challenging to predict which patients will have severe disease.
The bank, Europe's largest by market value, said the outlook for 2005 was "challenging to predict" in light of issues like terrorism and uncertainty about the American economy.
However, it is still challenging to predict the impacts of various gas transport mechanisms on well performance with arbitrary fracture geometry in a computationally efficient manner.
In addition, it is still challenging to predict fracture energies and crack-tip strain fields of soft tough materials.
In the face of rapid change and limited data, it is challenging to predict what Antarctica will do in the future.
This methodology will be particularly useful for designing RCTs aimed at evaluating combination prevention interventions in community-based RCTs, wherein an intervention׳s effectiveness is challenging to predict.
However, the mechanical behaviour of hybrid composites often shows hybrid effects which cannot be modelled by the rule-of-mixtures and are therefore challenging to predict and explain.
Because of the complexity of the core geometry and gap configuration, it is challenging to predict the flow distribution in the VHTR core.
Mine managers find it challenging to predict changes in the level of acceptance of their mining projects due to changes in associated social, environmental and technological factors.
Acute kidney injury (AKI) after cardiac surgery is associated with poor outcomes, but is challenging to predict from information available before surgery.
Yet because a lawsuit involving medical machine vision would be a matter of first impression with no clear precedent, it is challenging to predict exactly how a court would handle physician liability.
