However, in the current global neoliberal economy, this approach is often challenging to nearly impossible when the target population of the innovation does not represent a viable market, such as patients suffering neglected diseases or marginalized people living in extreme poverty in low-income countries.
So we've reached a period of time where I praise him and encourage him to do what he knows how to do right rather than challenging him on the things he loves to do, which are to challenge the impossible or to reach a certain degree of difficulty a lot of times.
As noted by Smith (2014), tools can provide a scaffold for teacher learning, "a structure that allows them [teachers] to do something that would otherwise be challenging or impossible to do" (p. 3).
The recognition of inferior vena cava filter related complications has motivated increased attentiveness in clinical follow-up of patients with inferior vena cava filters and has led to development of multiple approaches for retrieving filters that are challenging or impossible to remove using conventional techniques.
In the field of plasmonics, many unique structures have been demonstrated which would be challenging or impossible to fabricate using any other technique.
Our MPCD software enables simulations of mesoscale hydrodynamics at length and time scales that would be otherwise challenging or impossible to access.
Third, it often is challenging or impossible to determine the extent of alcohol involvement in health outcomes.
This analysis of the repressilator network in phase space provides an example for an experimental characterization that would be challenging or impossible to perform in a cellular environment.
Physical, cognitive, and clinical problems accumulate over time and tasks that once could be done without the help of others become challenging or impossible to perform.
Unfortunately, degrons and many mutant alleles in SPB components destroy SPB structure, and it is challenging or impossible to sort out primary versus secondary effects based solely on localization data.
