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It is challenging to design such a steam generator.
Water pollution permit systems are challenging to design and implement.
It is challenging to design numerical methods that can efficiently handle both difficulties.
Thus it is challenging to design a versatile scheduling policy that is effective in all circumstances.
Trials are challenging to design and it can be difficult to recruit patients, but with careful planning and good communication they are made possible.
However, it is challenging to design the VMS messages since the population possess different cultural, linguistic, and social backgrounds.
However, it is challenging to design such a platform to host multiple heterogenous and often highly customized virtual networks.
However, it is challenging to design experiments that unequivocally prove the advantageous effects of regulated cell death on immunity.
New residents enter emergency medicine (EM) residency programs with varying EM experiences, which makes residency orientation programs challenging to design.
It has been well-known that the Grassmannian codebooks are optimal for independent identically distributed channels, but it is challenging to design the optimal codebooks except for some special cases.
Though it is challenging to design a 3-DoS flexure mechanism from all selected motion type, the attempt to design flexure mechanisms with maximum degree of symmetry is still meaningful.
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