Sentence examples for challenging this issue from inspiring English sources

A paradigmatic example of how challenging this issue can be in clinical practice is the difficulty in rational prescribing for older patients with multiple chronic conditions and reduced life expectancy, when the likelihood of benefit and goals of care must also be considered in addition to satisfying the basic principles of optimal medication use in the elderly [ 3].

In order to challenge this issue, a software-type wave particle interaction analysis (S-WPIA) was implemented onboard the ERG.

Since former studies (Beckley, 2002; Schmidt et al., 1995; Stallard & Rayner, 2005; Van Vlierberghe et al., 2010; Welburn et al., 2002) were also able to find and confirm to a large extent all of the schemas they had investigated, it can be assumed that they would have been able to detect more schemas if only they would have challenged this issue.

"Changing beliefs and traditional practices takes time, and a development plan is needed to challenge this issue.

A widely accepted composite definition of timing is needed before an appropriate study challenging this major issue can be launched.

When the Scottish minister Fergus Ewing was challenged on this issue, he claimed that obliging landowners to register their estates in countries that aren't tax havens would risk "a negative effect on investment".

When challenged on this issue now, Redmond has a standard retort: "I just ask them if they've got kids... because every one of 67,000 schoolchildren in Liverpool were involved in a project at some stage.

But other wealthy taxpayers are also being challenged on this issue, our sources say.

But for those who will argue about the "authority of Scripture" it doesn't hold weight here because the Episcopal Church has always been challenged on this issue.

Because of the closeness of the bond between the two, there had long been rumours that their relationship was incestuous; in April 1922 Rose was directly challenged over this issue by her friend Lotta Hough.

Along with other challenges, this issue was appropriately dealt with by the Steering Committee and the Data and Safety Monitoring Committee and did not negatively affect trial results or conclusions.