Sentence examples for challenging target for from inspiring English sources
Consequently, KRAS is an exceptional albeit challenging target for targeted cancer therapies.
Therefore, potential sequestration of CO2 in shale formations leading to enhanced gas recovery (EGR) will be a promising while challenging target for the oil and gas industry.
Motivation: Protein protein interactions (PPIs) are a promising, but challenging target for pharmaceutical intervention.
The multifactorial and chronic natural history of type 2 diabetes makes it a promising, but challenging, target for therapeutic intervention in its early stages.
However, the Env trimer has proved to be a challenging target for 3D structure determination.
When West Indies were 180 for three with more than 12 overs to go, a challenging target for New Zealand to chase was on the horizon.
Naturally fractured reservoirs are challenging targets for chemical flooding because they typically have a high permeability contrast between the fractures and the matrix with a low matrix permeability.
Intracellular protein protein interactions (PPIs) are challenging targets for conventional drug modalities, because small molecules generally do not bind to their large, flat binding sites with high affinity, whereas monoclonal antibodies cannot cross the cell membrane to reach the targets.
They possess extraordinary specificity for a vast array of substrates and, as such, are considered promising, if challenging, targets for drug discovery [ 2].
However, the desired solubility phenotype itself is imperfect: in some cases the identified clones may express completely solubly [27], but we have often observed that some of the best constructs found for challenging targets show a mixed phenotype with expressed material in both insoluble and soluble fractions with the latter the minor component [38].
