On day 7 of DSS challenge, pathway analysis reveals six pathways to be characteristically associated with DSS in PPAR γ-expressing mice only.
Despite these challenges, pathway analysis helps to understand pathogenic processes on a molecular level.
Finally, the discussion will be presented regarding potential challenges, pathways, and opportunities.
Navigating the career labyrinth was possible for these women because they developed clarity of personal career goals, formed strong peer relationships within their networks and adopted a collaborative style that helped move them through dynamic and sometime challenge pathways.
Genetic engineering studies in plants have revealed that an increase in metabolic flux requires manipulation of most of the enzymes in a biosynthetic pathway, challenging the idea of a "limiting enzyme" [ 12].
Differences in patient size and body weight challenge the pathways of CT dose reduction.
Characterization of chemical stresses, such as MG and glyoxal, is challenging because numerous pathways (e.g., stress response and chemical detoxification) are involved.
Evaluating and understanding the impact of such an intervention is challenging because the pathways to impact are multiple and subject to effect modification [ 8].
Representatives of many of these chemical classes have been characterized, as have diketopiperazines and polybrominated pyrroles and phenols that arise from biosynthetic pathways challenging to predict using current algorithms.
