Sentence examples for challenging in the setting of from inspiring English sources

Large thrombus burden remains challenging in the setting of acute myocardial infarct.

The diagnosis may be even more challenging in the setting of known chronic liver disease and in patients taking multiple potentially hepatotoxic drugs.

While antibiotic-resistant strains are not expected to be clinically more virulent or challenging in the setting of acute outbreaks of gastroenteritis, MRSA may cause soft-tissue and other infections in the community that are difficult to treat.

Representativeness is especially challenging in the setting of farmworkers because of the numerous barriers that exist in defining the populations, temporal and geographic trends in exposures, range of job activities for a given worker, worker mobility, and other factors related to use/exposure to toxic chemicals, viruses, sun, co-pollutants, and noise.

That approach has recently been challenged in the setting of critical cardiac illness.

The diagnosis of AAD is challenging in the acute setting, and this prospective evaluation of the novel use of biomarkers for the rapid identification of AAD adds a promising tool to diagnostic algorithms.

The aim of this study was to compare the urine and plasma response 60 min after a 50 g oral glucose challenge in the setting of gestational diabetes mellitus (GDM) screening.

12 PI/r's and cobicistat pose unique challenges in the setting of steroid use, as they inhibit steroid metabolism via CYP3A4 and can drastically increase levels of prednisone and other steroids.

[ 45, 46] These discussions can be challenging in the ICU setting, however, due to lack of consistent prediction models, frequently evolving treatment courses, variations in patient/HCP belief systems, and the emotional stresses inherent to the ICU.

However, privacy preservation over incremental data sets is still challenging in the context of cloud because most data sets are of huge volume and distributed across multiple storage nodes.

Classic randomized clinical trials satisfying contemporary standards are extremely challenging to perform in the setting of established SE.