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Verifying the identity of a person using handwritten signatures is challenging in the presence of skilled forgeries, where a forger has access to a person's signature and deliberately attempt to imitate it.
Accurate localisation of the trachea is challenging in the presence of obesity, a short thick neck, prior irradiation or neck surgery, neck masses and any thoracic pathology causing tracheal deviation.
However, identifying this pattern of activity in a conventional EEG recording is challenging in the presence of HYPS due to the abundance of epileptiform discharges with varying focality and morphology [28].
Understanding the patient's wishes can be challenging in the presence of cognitive impairment.
Design optimization for the selection of dynamic models proves especially challenging in the presence of non-linear behavior (Balsa-Canto et al., 2008; Kitano, 2002).
Species tree estimation is challenging in the presence of incomplete lineage sorting (ILS), which can make gene trees different from the species tree.
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The outgrown cultures were then challenged
Fortunately, the symptomatology of reflux induced cough allows the clinician to identify cough of gastroesophageal origin.[ 8] The medical treatment of oesophageal reflux causing cough is challenging, particularly in the presence of non-acid reflux.
Further support for assuming TLR-independent perception of S. aureus by MEC comes from the previous observation that challenging pbMEC in the presence of 5 % FCS with supernatants from S. aureus activates AP1 - rather than NF-κB - governed regulatory networks [ 53].
Analyses of MP-12 titers in challenged cells in the presence of MAPK inhibitors indicated that activation of p38 represents a protective cell response while ERK activation controls viral replication.
The non-conservative character of this model poses however computational challenges in the presence of shocks.
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