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Perfusion of tubular and/or vascular structures within the tissue slice, to more accurately assess the intraluminal signalling pathways, would offer an obvious (yet technically challenging) improvement.
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One fundamental, but often poorly met, challenge for improvement efforts is that of convincing healthcare workers that there is a real problem to be addressed.
Six in-depth interviews with care farm staff will also be conducted to identify details of activities, support provided, challenges, improvements, their perceptions of the impacts of the care farm on offenders and their articulation of the purpose of the care farm.
Oakley, the former Knicks enforcer who was traded for Camby in June 1998, has belittled Camby's improvement, challenging him to post his typical double-double against them.
Improvement of the kinetic properties of P450s is likely to be challenging, though such improvements have been demonstrated in a microbial system [ 28].
It also identified managers who "have not been able to demonstrate sufficient understanding of failures" and have been ineffective in "prioritising, challenging and making improvements".
RNA isolation from these materials has been challenging, but significant improvements in RNA isolation protocols for archival formalin-fixed, paraffin-embedded (FFPE) tissues have been made in recent years.
Emerging themes from the in-depth interviews are summarized in Table 2 and grouped under thematic areas: 'existing good quality models in the Medical Department'weaknessessses or challenges of quality improvement' and 'suggestions for improvement'.
Although initially there was rapid improvement in all patients and the minimum A1C levels achieved were impressive (6.0 7.4%), sustaining that improvement was challenging for some.
The job is to show the political process can be a real tool for improvement, through challenging the might of the big institutions that have let down the public so badly.
Moreover, the antagonistic impact of this parameter on temperature and power consumption as the other design challenges of multiprocessor systems, make its improvement more challenging.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com