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Inspired by the music of jazz great Miles Davis, Belden produced two of his grandest projects: Miles from India (2008), a challenging fusion of jazz and Indian musicians and instruments, and Miles Español (2011), new compositions by former Davis sidemen, played by them and Spanish flamenco and folk artists.
American bands such as Queensrÿche and Dream Theater pioneered an often instrumentally challenging fusion of NWOBHM and progressive rock called progressive metal, with bands such as Symphony X combining aspects of power metal and classical music with the style, while Sweden's Opeth developed a unique style indebted to both death metal and atmospheric 70s prog rock.
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As noted above, having a mean fragment length shorter than twice the read length can challenge fusion detection tools that rely on fragments spanning fusion breakpoints with one read mapping entirely to each gene involved in the fusion.
The "Bold Moves" marketing program, now a year and a half old, included commercials that ran this year under the "Ford Challenge" and "Fusion Challenge" rubrics.
Epitope tagging of tubulins has been challenging, as GFP fusions at C-terminus of tubulin genes have failed to complement their corresponding null mutants in Saccharomyces cerevisiae [ 32].
Both GLuc and scFv proteins contain multiple disulfide bonds, and consequently the production of active and properly folded GLuc scFv fusions is challenging.
Identifying and quantifying the role played by SNAREs is challenging because the complex cellular fusion machinery involves many components.
A number of animals were protected from tumour challenging by the E7-Ii fusion gene [ 15].
Designing a sandwich fusion that produces a functional, fluorescent fusion protein is often challenging.
Post-fusion events, though challenging to explore, clearly need much more study.
The complexity of this region creates a variety of mechanical forces that challenge any fusion construct.
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