Sentence examples for challenging formulation from inspiring English sources

It's a challenging formulation as we approach 2017, flying in the face of what's become progressive common sense: the condescending conviction that only enlightened liberal stewardship stands between civilisation and the hordes of tabloid-reading Morlocks.

The study was span out with a challenging formulation design comprising ibuprofen compositions with varying particle size and a relatively low amount of the matrix former hydroxypropyl methylcellulose (HPMC).

The continuous process was provoked by a challenging formulation design, including variable powder characteristics and compositions of high and low amount of poorly soluble and poorly flowing drug substance (ibuprofen).

Like the gold standard, the performance metric is central and should be an integral part of the challenge formulation.

Redesigning a challenge can be laborious as it might imply obtaining data for a new gold standard and change assumptions that simplified the underlying biology and favored a good challenge formulation.

However, oral delivery is challenging, requiring formulations to overcome the harsh gastrointestinal (GI) environment and avoid tolerance induction to achieve effective protection.

Poorly water soluble drugs are challenging for the formulation scientists with regard to solubility and bioavailability.

"We're going to begin, as appropriate, to challenge these formulations of federal policy that are really changing the fabric of business in this country," said the House Rules Committee chairman, Rep. Pete Sessions (R-Tex.).

IL-4 can cause macrophages to switch from M1 to M2, thus helping muscle fibers heal faster; however, getting IL-4 to accumulate at its target site has proven challenging, and previous formulations that have attempted to solve this problem have not shown significant improvements in models of inflammation or injury.

This makes a physically consistent classical continuum model formulation very challenging.

Recent achievements in other sciences have allowed continual discovery of new natural mysteries and formulation of challenging goals for optics that require further development of modern concepts and running fundamental research.