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Blinding, especially double-blinding, is challenging for studies in which the intervention is being randomized [ 46].
We acknowledge that in the crisis context it would be challenging for studies to directly explore decisions about whether to take action with sexual assault survivors, which would be necessary to test the presence or absence of this mechanism.
Defining the circulating population is particularly challenging for studies of S. Typhi, as this organism is monophyletic and sequence diversity is limited [ 20].
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So we barely face any selection bias, which can be especially challenging for survey studies including cognitively impaired patients [ 36].
Recruitment is an essential part of any study, and it has been challenging for all studies, especially pediatric obesity studies.
However, reintegrating and strengthening these interpersonal relationships after repair were not challenging for our study population.
Based on the review, we discuss challenges for studies of usability and for research into how to measure usability.
This constant flux presents a huge technical challenge for studies of individual chromatophores, because such analyses require imaging techniques that can keep track of individual cells between frames of video footage.
The highly flexible nature of carbohydrate structures differs in many aspects from other biomolecules, posing significant challenges for studies employing computational simulation.
The financial market melt-down of the years 2007-2009 has posed great challenges for studies on financial economics.
Understanding the genetic variation of phenotypic responses to a range of environments (referred to as phenotypic plasticity or reaction norm) and its impact on selection and evolution has been a central challenge for studies in evolutionary genetics and ecology [1] [3].
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