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That allows us to get hold of some very challenging correlations that humans just can't do".
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Phenotypic heterogeneity makes phenotype-genotype correlations challenging or impracticable, as highlighted by deletions of 15q13.3 or 16p13.11 [20].
On the basis of our results, we cannot challenge the correlation between the PAX3-FKHR transcription factor and the expression of the MET and CXCR4 receptors.
Trying to challenge the correlation between treatment delay and outcome for the patient, different workgroups stated that a longer treatment delay does not cause a lower survival rate [ 2, 3, 6, 30].
To challenge this correlation, the data were split into a training and a test set, which produced an R for the test set of 0.61 (Fig. S1 †), confirming on comparison of the R in Fig. 2 that this correlation was not a product of over fitting.
Another scenario in which the lack of sufficient tissue availability has been challenging is the correlation of the phenotype in individual experimental animals with comprehensive gene expression profiles.
This observation is somewhat reassuring as susceptibility testing of molds is challenging and the correlation with clinical outcome is often debated.
Open cell foams are attractive materials for various industrial applications, but building accurate universal correlations is challenging due to their great geometrical complexity.
However, such correlations are challenging to interpret, as they are highly susceptible to overestimation caused by noise and bleed-through (Bolte and Cordelieres 2006).
Because these variables correlate with each other, untangling cause from spurious correlation is challenging.
Although the main concern of the paper is challenging the use of correlation for validating language tests/test score meaning, a brief look at the meaning of correlation seems desirable at this point.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com