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As a result, past nominees for OIRA administrator have faced challenging confirmation processes, and the office has gone without political leadership for months and even years.
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mystery fire which gutted the premises, said they had also received "bomb threats" but are challenging the confirmation of a compulsory purchase order that could force them to make way for a new 56,000-capacity stadium complex.
Regardless of the target organism, all researchers using sequence-specific nucleases face similar challenges: confirmation of the desired on-target mutation and the detection of off-target events.
On the other side of the divide, Jonathan Haidt, a psychology professor at the University of Virginia, said of Mr. Sperber and Mr. Mercier, "Their work is important and points to some ways that the limits of reason can be overcome by putting people together in the right way, in particular to challenge people's confirmation biases".
While President Obama had said that he wanted a justice with empathy, Judge Sotomayor was repeatedly challenged during her confirmation hearings as to whether she would be empathic when judging cases.
This paradigm was recently challenged by the confirmation that another regimen, which includes a combination of 5-FU, leucovorin, oxaliplatin and irinotecan (FOLFIRINOX) was superior to single agent gemcitabine in the metastatic setting [ 5].
However, this last exercise would require both the establishment of an in vitro culturing system for A. willeyana (an exercise that has many technical challenges) and confirmation that drugs developed for the modulation of the autophagy pathway in other organisms also function as expected in the deeply evolutionarily divergent A. willeyana.
A challenging aspect of the procedure is the insertion and confirmation of at least 2 guidewires into the cyst.
However, due to the scarcity of CCSCs among hematologic cells in the blood and the complexity of the phenotype confirmation process, CCSC research can be extremely challenging.
But Scott Wallace, a Democrat challenging Fitzpatrick in Pennsylvania's 1st Congressional District, sees the award as confirmation of Fitzpatrick's questionable commitment to programs for seniors.
Nevertheness, the confirmation of prostate cancer susceptibility genes has been challenging.
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