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However, the synthesis of nucleosides and its corresponding analogues remains a challenging and time consuming process.
However, they rely on the surgeon's ability to tie secured knots, which is a challenging and time consuming process.
Analog circuit design has become a very challenging and time consuming process for circuit designers due to increased non-idealities and worsening variability phenomena.
The microscopist is obliged to keep the imaging area centered during tilting as well as to maintain accurate focus in the tilted image while minimizing the overall electron dose, a challenging and time consuming process.
This makes comparison of different datasets a challenging and time consuming process.
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Altogether, this is a very laborious and time consuming process.
Drug development is an expensive and time consuming process.
However, it is a labour intensive and time consuming process.
Recombinant, soluble forms of MPs have been successfully employed as antigen sources for antibody engineering, but heterologous expression and purification of soluble MP fragments remains a challenging and time-consuming process.
"Obtaining appropriate evidence to put before the courts in matters such as this is a challenging and time-consuming process, but the AFP and its partner agencies will not hesitate to investigate and prosecute individuals who choose to ignore the repeated warnings of the government, police and the community".
That's why health departments often require patients to take their pills in front of a health care provider a logistically challenging and time-consuming process.
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