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Considering that CLEM is a very valuable but technically challenging and time-consuming method, accurate protocols are needed to simplify the efforts of researchers who are willing to apply this method for their own purposes.
DDH is technically challenging, labor intensive and a time consuming method [ 5, 6].
These methods are often complicated, technically challenging, and time consuming.
However, these methods yield moderate accuracy [2] or are at least technically challenging and time consuming [9].
However, these are expensive and time-consuming methods.
Forming a functional coalition government may prove more challenging and time consuming.
Thus, evolving scheduling components is challenging and time consuming.
Surgical reconstruction of maxilla is technically challenging and time consuming.
Microsurgical reconstruction of maxilla is technical challenging and time consuming.
Processing these dynamic big graph data is very challenging and time consuming.
However, the synthesis of nucleosides and its corresponding analogues remains a challenging and time consuming process.
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