When Sonne started the company, one of his biggest challenges was determining who would be able to thrive as a tech consultant in an office environment.
Protection from wt virus challenge was determined by measuring inhibition of wt viral replication in nasal washes and in lung tissue.
Mortalities were recorded twice a day and the "time to death post-challenge" was determined for each bioassay.
The end point of the challenge was determined by the pediatric pulmonologist as positive in 35/36 children.
The total number of coughs evoked by each concentration of citric acid both during the 5 minute challenge and during the 5 minutes following the challenge was determined.
Heart rate after pharmacological challenge was determined over a 30-min time course and was measured when it had reached a steady state.
The mice were chow-fed and the transcriptome of three female mice from each BXD line after CCl4 challenge was determined with Affymetrix Mouse Gene 1.0 ST microarrays.
The Δmax cortisol after corticotropin challenge was determined as a marker of adrenal gland reserve response by subtracting the cortisol baseline value from the 60 minutes cortisol value.
In order to analyse αT2ib function, NF-κB driven reporter gene activity in HEK293 cells overexpressing both mTLR2 and αT2ib upon TLR2 specific challenge was determined.
To further investigate the molecular mechanism of anti-apoptotic activity of DG, the nature of the cytochrome c release after a H/R challenge was determined.
