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Municipalities face the greatest challenges to define the deterioration processes and the factors that can affect the rate of deterioration.
Process integration involves synthesis challenges to define biorefinery portfolios and systems integration to combine fermentation, stripping, adsorption, and distillation.
Consequently, attempts to identify a novel lipid mediator generated from macrophages and challenges to define its actions and biosynthesis led to the discovery of a novel group of DHA-derived resolvents, maresins [ 99].
However, it is anticipated that future data submissions will contain many more complex gene expression profiles and large-scale single nucleotide polymorphism maps (e.g., from whole genome scans), which will present new challenges to define the analytical and clinical validity of such new and highly complex bio-marker sets.
For example, the clinical decision level for cTn assay A achieving a specificity of 90% in patients with renal dysfunction cannot be reliably extrapolated from observations made with cTn assay B. To some extent, this requirement is explained by biochemical differences among the cTn assays and the challenges to define a healthy reference population to determine the 99th percentile.
Similar(53)
The scale of the challenges to defining the incidence of injuries was found to be manageable.
But we are not faring well with the cognitive challenge to define this phenomenon.
It might be a bit of a political challenge to define happiness as a legitimate policy objective.
While it is challenging to define precise triggers ex ante, we might be able to determine them in principle.
Due to the variety of existing methods, it is challenging to define an appropriate method for each decision problem.
It is a real challenge to define and to design diagnostics systems considering the constraints imposed by these service systems.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com