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Other challenges to curation include evolving standards.
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The continued increase in article number, data types and data density (within each article) is an on-going challenge to curation management.
While these and other issues provide notable challenges to the curation team, the InnateDB curation system, its detailed guide on the curation process, and regular meetings to discuss potential pitfalls, ensures that InnateDB has a very high standard of curation.
This iterative development cycle provided both unique benefits and challenges to the eagle-i Curation team.
The straight gray line is the break-even line, where curation effort equals to curation hits.
V.C. contributed to curation and performed model analysis.
One of them was exclusively related to curation aspects.
The first reason for FP is due to curation rules.
Rather than considering manual annotations and computational predictions as separate sets with little relevance to each other, the challenge for biological curation is to find efficient ways to compare them in order to ensure that the set of annotations for each gene is as high-quality, complete, and current as possible.
We have documented several informatics challenges during the curation of Medicago genome and presented our solutions to those challenges.
Another key challenge for curation is the fact that molecules can have several common names, which can lead to ambiguity in annotating the participant molecules in an interaction.
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