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Here there is a willful disregard of evidence--or an incapacity to understand it that challenges the premises of demonstrability ineffective ideas like supply side economics.
The present study is pioneering in the sense that it challenges the premises of former models.
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Her version of her father's past challenges the premise of "Father Joe": that Tony Hendra found deliverance through faith and atoning for his failings.
As Nick Bostrom, the head of the Future of Humanity Institute at the University of Oxford and a leading transhumanist thinker puts it, transhumanism "challenges the premise that the human condition is and will remain essentially unalterable".
Redefining consumption in this way challenges the premise underlying current market structures, in which legal mechanisms such as confidentiality agreements and intellectual property rights are often invoked to shroud the details of production from the inquiring public.
(Bernstein challenges the premise of Edward Said's "Orientalism," arguing that "the eroticized vision of the East carries a hard kernel of truth, which the followers of Said are loath to acknowledge").
An article in the current issue of the New England Journal of Medicine severely challenges the premise that mold and bacteria cause childhood asthma.
…Though the theory of intelligent design does not identify the agent responsible for the information the signature in the cell, it does affirm that the ultimate cause of life is personal...The case for intelligent design challenges the premise of the materialist credo and holds out the possibility of reversing the philosophy of despair that flows from it.
Practically no one challenges the premise, which we're all taught from childhood, that acting for one's own benefit is morally tainted, while sacrificing for the benefit of others is the essence of moral virtue.
Suspending our disbelief about the truth of a story in this way involves 'cognitive estrangement', a process whereby we wilfully lack the knowledge to challenge the premises on which a narrative is built.
Troy was tearing apart the union data long before he began challenging the premises of unionism.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com