Among the challenges, the difficulty of writing effective contracts with employees is an understudied cause.
Applying fibril-forming peptides in nanomaterial design is still challenged by the difficulties in understanding and controlling how fibrils form.
The quest to surf on artificial waves has long been challenged by the difficulties of mastering the fluid dynamics, engineering and mechanics necessary to mimic the ocean.
If managing the reputation of apprenticeships felt an old challenge, the difficulties of managing an institution's reputation in the age of the internet felt very new.
Australia's political challenges underscore the difficulties the Paris Agreement now faces.
Nintendo's challenges highlight the difficulties of navigating a fast-changing industry.
Developing a course which might be self-taught raises design challenges besides the difficulties of providing an international overview of copyright which varies among countries.
Generic challenges included the difficulties students experienced with regards to the new terminology; aspects of finding the literature; as well as understanding statistical concepts and critical appraisal.
24 Mixed method research is challenging, including the difficulty of reconciling differing philosophical paradigms, commonly referred to as 'paradigm wars'.
In the context of conidial germination, the identification of reliable reference genes was first challenged by the difficulty of producing good quality RNA samples.
