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The underlying challenges of system design, operation and economics also lack proper understanding.
Dealing with device diversity has always been one of the important challenges of system administration.
The ultimate challenges of system modeling concern designing accurate yet highly transparent and user-centric models.
Challenges of system calibration at depth, temperature and pressure artifacts, and system control through over 4 km of cable were successfully overcome.
In Multi-Core Technology epoch, Network on Chip (NoC) architectures has been acknowledged as a solution to solve the design challenges of System on Chips (SoCs).
The challenges of system integration are compounded by the fact that evaluations of mHealth (and eHealth) interventions tend to focus on feasibility, rather than impact and cost-effectiveness, making it difficult to conclude on benefits [ 4, 13- 15].
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Electrostatic discharge (ESD) protection design for mixed-voltage I/O interfaces has been one of the key challenges of system-on-a-chip (SOC) implementation in nanoscale CMOS processes.
Büscher et al. [19] discuss the challenges of systems such as ours, from a social perspective.
And that, in a nutshell, may define the opportunities and challenges of systems biology, as a field of science and as a career.
One of the challenges of systems engineering research is that the expertise and the application happen "in the field".
Kitano [1] also noted that new tools, ranging from experimental devices to software and analytical methods, are required if we are to meet the challenges of systems biology.
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