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One of the challenges of formulating gradient elasticity theories is to keep the number of additional constitutive parameters to a minimum.
In their review, Miyake and Bleier discuss the challenges of formulating drug targeting strategies to bypass the blood-brain barrier and deliver therapeutics to the central nervous system (CNS).
Vegetarian proteins can be economically produced if one understands the challenges of formulating, manufacturing and logistics of taking vegetarian proteins to market.
One of the challenges of formulating waterborne coatings is achieving an acceptable balance of properties both during the film application and drying process as well as in the final film.
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But as HIP Investor CEO R Paul Herman argues, the challenge of formulating an assigned value to human beings, and even the risk that such figures could be manipulated by dodgy financial analysts, does not mean that accounting standards should not be updated to reflect the realities of 21st century business.
"We repeatedly witness the challenges to formulating a stable system of governance that works towards the long-term improvement of everyone and that won't be derailed by short-term interests of the powerful or wealthy".
Challenging mind traps by means of formulating alternative realistic-optimistic thoughts on the spot, and searching for proof of your thoughts, is practiced.
Perhaps the premier challenge for formulating appropriate mathematical models is the complexity of signaling networks, especially due to formation of multiple complexes and many different post-translation protein modifications.
The challenges of multidisciplinary care involving diverse philosophical and clinical traditions bring forth the opportunity and necessity of formulating new models of proactive polypharmacy focused on patient safety, therapeutic efficacy and evidence-informed clinical-decision making.
Thus it became a challenge to formulate a philosophical theory of mathematics that was free of platonistic elements.
This claim raises empirical questions concerning the nature of human/non-human primate differences [Crow, 2004a; Rogers, 2004], and introduces a challenge to formulate a saltational account of the speciation process [Crow, 2005].
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