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One of the major challenges in developmental biology is to understand the regulatory events that generate neuronal diversity.
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A major challenge in developmental biology field is to decipher the molecular mechanisms involved in cellular differentiation and to understand the processes that control and regulate genes expression.
Understanding the signals that guide neuronal development and direct formation of axons, dendrites, and synapses during wiring of the brain is a fundamental challenge in developmental neuroscience.
Understanding how signals through gene expression generate patterns and govern ontogenic timing is a crucial challenge in developmental biology.
One challenge in developmental biology is to identify and understand the overall developmental role of genes involved in the temporal patterning of genetic programs.
Understanding the dynamics of stem cell differentiation processes at the molecular level is a central challenge in developmental biology and regenerative medicine.
Different genes code for the various proteins associated with these two properties, and understanding the behaviour and properties of stem cells in detail is a major challenge in developmental biology.
Understanding how disparate cell types execute specialized cell behaviors is therefore a key challenge in developmental biology and will require us not only to delineate gene regulatory networks, but also to associate particular genes in the network with particular cellular machinery.
We currently face significant challenges in understanding developmental health risks associated with the thousands of diverse compounds entering the environment (Martin et al. 2009b).
This review explores challenges and opportunities in developmental physiology outlined by a symposium at the 2014 American Physiological Society Intersociety Meeting: Comparative Approaches to Grand Challenges in Physiology.
The age-varying relationships, illustrated here, demonstrate the challenge in studying developmental data.
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