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Each of these repeat classes exists as large tandem arrays which pose significant technical challenges in assembly accuracy.
These repeat classes exists as large tandem arrays, likely in the form of higher-order repeat units of slight variants of the main consensus repeat which pose significant technical challenges in assembly accuracy [ 30, 31].
Indeed, it is well recognized that there is room for better algorithmic use of the data, especially for repetitive regions, which are one of the primary challenges in assembly.
In terms of sequence coverage alone, the NG sequencing is a dramatic advance over capillary-based sequencing, but NG sequencing also presents significant challenges in assembly and sequence accuracy due to short read lengths, method-specific sequencing errors, and the absence of physical clones.
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While this strategy was proved to be successful for EST assembly, there are significant challenges in transcriptome assembly from high-throughput sequencing data that are caused by the shorter reads.
Thus, the presence of coverage gaps for rare variants introduces additional challenges in the assembly process, making rare genomes unreachable by assembly tools.
Huge volume of data and high data complexity are the main challenges in metagenomic assembly.
That's because of challenges in the assembly process, according to a new report by the Wall Street Journal which cites an unnamed Foxconn executive as its source.
One of the basic challenges in precision assembly is the need for very high accuracy over a large range of motion.
Manufacturing of the iPhone 5 might have gone better than expected (though was a shortage of the device after it was first released due to challenges in the assembly process), and some analysts have speculated that Apple plans to launch one or more new iPhone models by this summer.
AlignGraph's functionalities are unique by solving several challenges in improving assembly results.
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