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Based on a iterative strategy of proteomic analysis, data interpretation and sytstematic challenges, hypothesis can be developed and modified, which will eventually lead to the generation of new knowledge.
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The current study, attempts to replicate the findings of the original study, and challenges hypotheses presenting a "one size fits all" model of HEV.
The Markeys were looking for confirmation of a phenomenon called the challenge hypothesis.
This suggests that males involved in a competition will experience a rise in testosterone levels if they win, and a fall if they lose.The challenge hypothesis was first advanced to explain the mating behaviour of monogamous birds.
"I like this experiment," says John Wingfield, an environmental endocrinologist at the University of Washington in Seattle who developed the challenge hypothesis.
We tested the challenge hypothesis for the hormonal regulation of aggression in chicks of the black-headed gull, Larus ridibundus.
The levels of testosterone, a hormone tied to aggression, should go up whenever males' status is threatened, according to an idea called the "challenge hypothesis".
This is the first report showing that the challenge hypothesis as established for adult birds, is also applicable for aggressive behavior in young birds outside the sexual context.
Most of these predictions were supported by the review of current research, although most studies were not designed to specifically test the challenge hypothesis.
Research on testosterone-behavior relationships in humans is assessed in relation to a version of the challenge hypothesis, originally proposed to account for testosterone-aggression associations in monogamous birds.
The "challenge hypothesis" [5] attempts to explain the variable linkage of T and aggression during the breeding season.
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