Sentence examples for challenges combined from inspiring English sources

Provenge was hailed as breakthrough for the cell therapy industry [ 1] but ultimately a combination of manufacturing and marketing challenges, combined with the emergence of more affordable and less complicated competition led it to underperform expectations [ 34, 35].

The magnitude of these challenges, combined with many others, has caused some early proponents of tokamaks to question whether the design itself is intrinsically flawed.

The first warning signs emerged in 2009 when the Commons defence committee warned that "persistent overoptimism and underestimation of the technical challenges combined with inappropriate commercial arrangements" would lead to rising costs.

Nevertheless, current and impending challenges combined with technological progress are bringing new participants to the health and care market place, each offering insight, ideas, innovation and resources as well as different relationships with the general public.

But the mainstream thinking, I mean the top leadership, is still very sober-minded about China's own power and influence, and they are very conscious of China's internal challenges combined with external challenges".

Such challenges combined with unpredictable rainfall and changing temperature (Campbell et al. 2005; Sandford 2006) leave villagers vulnerable to economic disasters.

The paper addresses both of these challenges combining experimental innovations with a systems engineering approach.

BamBrogan says that they'll look to source the best available engineers because they have a significant technical challenge, combined with a desire to actually change the world in very practical and impactful ways.

In vivo, ALI was induced by intranasal endotoxin-challenge combined with GW280264X treatment or endothelial adam17-knockout.

One of the more successful activities for addressing this challenge combined student-created problems and collaborative writing with the wiki tool in our Sakai learning management system.

These results highlight the potential use of an exercise challenge combined with microarray gene expression analysis in identifying gene ontologies associated with CFS.