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She is a modern philosopher of beauty who seemed genuinely uplifted (and challenged) by the notion that someday older women might take to the runway.
As men, they may still be challenged by the notion of men's rooms where they compared whose "member" is larger, and who can throw their "load" further.
This view has been challenged by the notion that such signals are part of the pervasive transcription of the genome and not necessarily associated to known genes [ 9, 12, 15].
However, both the genetic background of the host and the dietary environment are responsible for the occurrence of metabolic diseases by shaping the gut microbiota, even if this concept can be challenged by the notion of diabetic-sensitive and diabetic-resistant mice.
This hypothesis, as it applies to tumor angiogenesis, is somewhat challenged by the notion that the majority of intratumoral neovessels seem to lack periendothelial smooth muscle cells [ 67], suggesting that there may be additional roles for the TGF-βs in tumor angiogenesis.
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This linear framing of innovation is being challenged by the notions of an evolving non-linear innovation.
Also, classic notions of clinical utility are challenged by the newer notion of 'personal utility.' Consideration of test characteristics is essential to any valuable discourse on the ELSI of personal genome testing for multifactorial diseases.
GILLESPIE: To take out the part where the premise of the question was challenged by the President where he rejected the notion.
This notion is challenged by the results presented here, which, instead, indicate that the translation of at least certain viral mRNAs can specifically be targeted for therapeutic intervention.
During the Tai outbreak in Côte d'Ivoire, carnivorous behavior (especially consumption of Colobus monkeys) was the suspected source of infection (12 ), but this notion is challenged by the infection of gorillas, which are almost exclusively herbivorous.
This notion is challenged by the observation that loss-of-function mutations in components of the IIS pathway can reduce biomarkers of aging and extend lifespan in worms, flies and mice (Fontana et al, 2010; Kenyon, 2010).
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