Sentence examples for challenged bone from inspiring English sources

DOI: http://dx.doi.org/10.7554/eLife.04066.008 To ascertain if NEU1 is the therapeutic target of Neu5Gc2en in endotoxic shock, we challenged bone marrow chimeric mice with a lethal dose of LPS (200 μg for WT chimera and 400 μg for Neu1 −/− chimera, see Figure 4G) and determined the effect of Neu5Gc2en, administrated at 6 hr after LPS challenge.

With the new project, the team are hoping to provide an answer, challenging bone experts around the world to scrutinise the skulls and complete questionnaires on their osteological observations, as well as sharing information about the type of device they are viewing the virtual skulls on.

Our results indicate that the hybrid delivery system resulted in consistent bony bridging of the challenging bone defects.

Overall, our results indicate that the hybrid alginate/nanofiber mesh system is a promising growth factor delivery strategy for the repair of challenging bone injuries.

Bone morphogenetic protein-2 (rhBMP-2) has been used to promote spinal fusion and repair of challenging bone defects; however, the current clinically-used carrier, absorbable collagen sponge, requires high doses and has been associated with adverse complications.

And these results may suggest an effective strategy to employ the cell-based therapies in the treatment of challenging bone disorders in diabetes.

Therefore, our study urges further investigation of the bone marrow niche of the single or double knockout mice as well as on their involvement in experimental models challenging bone development or healing.

The resulting bacterial strains were grown in culture and used to challenge bone marrow macrophages seeded into 96-well microtiter dishes having optically clear bottoms, followed by fixation and probing by indirect immunofluorescence with anti-SidC serum and monoclonal anti- L. pneumophila (Fig. 1, Experimental procedures).

A trip to #Mars will challenge bones.

This concept has been challenged by bone marrow transplantation experiments in mice, demonstrating generation of cells of different phenotype after transplantation of marrow or muscle cells.

Norris (p. 214, [19]) challenged the bone conduction notion because it would not provide differential frequency information or cues for directional discrimination.