Sentence examples for challenge which impairs from inspiring English sources

The spread of microbial drug resistance is a global public health challenge, which impairs the efficacy of antimicrobial agents and results in substantial increased illness and death rates and healthcare-associated costs (1 – 3 ).

Resistance to imatinib represents a clinical challenge and is often a result of point mutations causing a conformation change in Bcr-Abl, which impairs imatinib binding.

The nicotine causes blood vessels to narrow on the surface of your face and hands, which impairs blood flow.

But he also wrote about the "psychological censorship [rather than the exercise of the law] which impairs the human heritage".

Thus oxygen supply is reduced, which impairs lipid oxidation.

Tooth extraction induces residual ridge resorption which impairs function and aesthetic of dental prostheses.

Second, it's well documented that healthcare costs are causing people to spend less on retail which impairs their bottomline.

Because toxicities related to the administration of high-dose IL-2 have been a major challenge, which previously impaired broad application of these methods, these results can stimulate the initiation of ACT programs at other institutions.

In March 2001, she suffered a further stroke, which impaired her mobility and sight.

Impaired response inhibition is a behavioral trait of which impaired satiety may be one manifestation.

Screening NOD mice for elevated blood glucose allowed us to efficiently select mice with impaired response to glucose challenge, which is indicative of the most advanced stages of insulitis (Figure 6A) [27].