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A major challenge to investigating independent contributions of WMHs in AD is disentangling their contributory role to cerebral atrophy.
An important challenge to investigating the potential link between antidepressant drug therapy and future diabetes risk concerns the assessment of diabetes.
One challenge to investigating multifunctional enzymes is that several reactions take place sequentially in a very short time scale and therefore analysis of one specific reaction is usually difficult.
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PET scanning has limited spatial resolution, and therefore, it remains a challenge to investigate the arterial wall.
This rises a new challenge to investigate whether by adopting the same optimization strategies as those used for high-end GPU is suitable to design an embedded system-based SLAM applications.
Finally, it is still a big challenge to investigate the finite-time anti-synchronization of neural networks with discontinuous dynamic behaviors; these problems will be considered in the next papers.
However, urban environments have a complex nature to model and they provide a challenge to investigate the current limits of automatic digital surface modeling from high resolution satellite imagery.
It is the next challenge to investigate other types of tumor model including the relationship between glycolysis and oxidative phosphorylation and to evaluate the changes in perfusion and oxygen metabolism after the anti-tumor therapy or modulation of perfusion and hypoxia.
In conclusion, these analyses revealed PUM- and possibly cell/tissue-specific functional attributes among the potentially regulated messages, and it will be a future challenge to investigate the functional roles of PUM regulation on key targets.
Others have taken up the challenge to investigate gender differences within households using non-monetary indicators (Cantillon and Nolan 2001).
Therefore it is a challenge to investigate gene/environment interactions for major ecological interactions of this cladoceran.
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