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With the limited control over the internal structure of the electrode, it also often poses a significant challenge to elucidate the structure-property relationship between components within the electrode.
Oral processing of solid foods is a highly dynamic and complex process; this creates a major challenge to elucidate the role of various components, hierarchical structures and phases on foods' organoleptic properties.
Although X-ray crystallography remains the most versatile method to determine the three-dimensional atomic structure of proteins and much progress has been made in model building and refinement techniques, it remains a challenge to elucidate accurately the structure of proteins in medium-resolution crystals.
Ultimately, the strength of imaging genetics and genomics lies in their translational and integrative potential with other research approaches (e.g., nonhuman animal models, psychiatric genetics, pharmacologic challenge) to elucidate brain-based pathways that give rise to the vast individual differences in behavior as well as risk for psychopathology.
Nonetheless, none of them contain annotations about the P. falciparum target(s) involved, making it a challenge to elucidate the mode of action (MoA) of the compounds in the dataset, and hence, making the dataset difficult to interpret.
It will be an important challenge to elucidate the precise mechanisms and role of caveolin tyrosine phosphorylation in the regulated endocytosis of the insulin receptor by caveolae.
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A challenge to elucidating these mechanisms has been the difficulty encountered in the development of experimental whole animal models of arsenic carcinogenesis.
Future research is particularly challenged to elucidate the specific molecular and cellular mechanisms that may underlie the observed learning-induced alterations in brain structure.
This raises interesting challenges to elucidate sufficient information from these networks for therapeutic benefit in medical bionics.
Therefore, challenges to elucidate the roles/significances of protection mechanisms in plant salt tolerance including morphological barriers at molecular, cellular and whole plant levels in further depth will be crucial to develop high-yielding salt-tolerant cultivars.
This study was performed to delineate functional, structural and immunological airway changes after cessation of long term challenges to elucidate factors contributing to the development of prolonged lung function changes.
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