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One key challenge to defining human embryo phenotypes relates to the unclear and often highly interactive relationships amongst variables pertaining to patient characteristics, clinical infertility diagnoses, IVF treatment protocols, and observed embryo characteristics.
A further challenge to defining the pathology of disease is the intracellular location of the target antigens, thus raising questions regarding accessibility to maternal antibodies.
Therefore, there is no scientific basis to determine what aspect of RF exposure should be modified, a further challenge to defining precautionary measures.
A critical challenge to defining a safe level of exposure to arsenic is to establish how the obvious causal cancer link due to high arsenic exposure, which is widely accepted, can be extrapolated to what we can expect from lower exposure [ 24], which is much debated.
Seabed data/maps often represent these areas as "white ribbon" zones, where sparse data coverage presents a particular challenge to defining and enforcing sustainable use of marine resources.
One challenge to defining art stems from the fact that contemporary artists frequently create with the intention of questioning, undermining, or rejecting values that defined art of the past.
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But we are not faring well with the cognitive challenge to define this phenomenon.
It might be a bit of a political challenge to define happiness as a legitimate policy objective.
It is a real challenge to define and to design diagnostics systems considering the constraints imposed by these service systems.
Clinical engineering faces today a great challenge to define the basic requirements a person must attend to be called clinical engineer.
In response to Ferris' (2003) challenge to define the parameters of the research design and methodology and in order to isolate the effectiveness of feedback, Guenette (2007) examined whether feedback is pedagogically correct.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com