Sentence examples for challenge the expressions from inspiring English sources

We further used Real-time PCR to study the expression of these genes with or without challenge by microbial pathogens, demonstrating that 4 days after challenge the expressions were gradually down-regulated, but up-regulated again after the fifth day (Figure 11A, 11B).

Two model proteins with different complexity were selected in order to challenge the expression systems in different ways.

However, when we challenge the miRNAs expression of singular CLL cases versus the median value recorded in reactive lymph node, we observed a significant higher occurrence of downregulation of hsa-miR-16-1-3p hsa-miR-16-1-3p hsa-miR-16-1-3p hsa-miR-16-1-3p hsa-miR-16-1-3p001; Finure 5; Supplementary Table  1 available online at http://dx.doi.org/10.1155/2013/715391).

During the first 24 hr after pathogen challenge, the expression level of VpBD mRNA was obviously up-regulated and reached 7.4-fold compared to that of control group.

Similarly, at day 15 (1 day after the first intranasal challenge), the expression of MHC II and costimulatory molecules were similar to naive lung B cells.

Upon Escherichia coli (E coli -LPS coli -LPS, the expression of challengecarbonic anhydrase II (CA II), along withesexpression-inflammatofy CFTRkines wandup-regulated in the primary carbonicof ranhydrasete epIIhelial CAlls.

In order to validate the RNA-seq data of the A. avenae challenge, the expression of a selection of genes showing statistically significant induction in response to A. avenae was confirmed by qRT-PCR and immunoblotting.

Interestingly, even after tumor challenge, the expression levels of total CTLA-4 in CD44hiCD8+ T cells, and the percentages of CD4+Foxp3+ Tregs in lung tumors, spleens, or lymph nodes were not reduced in the immunized SKAP55−/− mice (Fig 4F).

In comparison to the non-arthritic Balb/c mice with tumor challenge, the expression of COX-2 in the bones of the arthritic mice was significantly greater even without any tumor, which was undeniably augmented when these arthritic mice were challenged with the 4T1 tumors but not with TUBO (data not shown).

As TCR signaling is central to immune function and was affected by BASE challenge, the expression of six genes involved in this pathway (TCRδ, CD3E, ZAP70, TRAT1, LAT, LCK) was analyzed over a time course following BASE challenge (10-12-24 MPC) by qPCR.

However, there are several studies that present results that challenge the hypothesis that reduced expression of the desmosomal cadherins leads to a more aggressive and metastatic tumour phenotype.