Sentence examples for challenge the expression from inspiring English sources

Two model proteins with different complexity were selected in order to challenge the expression systems in different ways.

During the first 24 hr after pathogen challenge, the expression level of VpBD mRNA was obviously up-regulated and reached 7.4-fold compared to that of control group.

Similarly, at day 15 (1 day after the first intranasal challenge), the expression of MHC II and costimulatory molecules were similar to naive lung B cells.

Upon Escherichia coli (E coli -LPS coli -LPS, the expression of challengecarbonic anhydrase II (CA II), along withesexpression-inflammatofy CFTRkines wandup-regulated in the primary carbonicof ranhydrasete epIIhelial CAlls.

In order to validate the RNA-seq data of the A. avenae challenge, the expression of a selection of genes showing statistically significant induction in response to A. avenae was confirmed by qRT-PCR and immunoblotting.

Interestingly, even after tumor challenge, the expression levels of total CTLA-4 in CD44hiCD8+ T cells, and the percentages of CD4+Foxp3+ Tregs in lung tumors, spleens, or lymph nodes were not reduced in the immunized SKAP55−/− mice (Fig 4F).

We further used Real-time PCR to study the expression of these genes with or without challenge by microbial pathogens, demonstrating that 4 days after challenge the expressions were gradually down-regulated, but up-regulated again after the fifth day (Figure 11A, 11B).

However, there are several studies that present results that challenge the hypothesis that reduced expression of the desmosomal cadherins leads to a more aggressive and metastatic tumour phenotype.

Investigations to challenge the impact of cyclin D1 expression revealed that cyclin D1-positive tumours associated with significantly lower preoperative PSA values, indicating that cyclin D1 status may influence tumour marker expression.

H/R challenges induced the expression of Bax and cleaved caspase-3, whereas suppressed the expression of Bcl-2; however, the effect was diminished in cells transfected with AdshTRAF1 and was greatly increased by transfection with AdTRAF1.

Nonetheless, identifying gene expression profiles associated with xenobiotic metabolism remains challenging because the expression of genes encoding the xenobiotic enzymes is highly variable within an individual because it may change over time [ 15].