Sentence examples for challenge strains for from inspiring English sources
Accordingly, C-PGammer and GL8-like viruses may serve as biologically relevant challenge strains for trials of candidate vaccines.
This strain of P. falciparum also produces gametocytes and its sensitivity to chloroquine has made it an excellent choice as a challenge strain for human Phase 2a vaccine trials [30].
The challenge strain of E. coli O157 H7 selected for the experimental infection was 438/99.
The methicillin-resistance was also correctly identified for all challenge strains.
The sensitivity of the differential assays for the challenge strains were evaluated using a standard curve prepared from a serial 10-fold dilution of viral RNA from the corresponding viral strain that had been quantified using a pan-CSFV PCR [ 27].
The BHN97Δ ftsY vaccine resulted in significantly decreased bacterial titers in the blood following infection for all three challenge strains (Fig 5B, D, F).
In contrast, primers used in the assays for detection of challenge strains CBR/93 or UK2000/7.1 (HE5 and HE4.1/4.2) amplified all strains equivalently, therefore the discrimination by these assays depended entirely on the specificity of the cognate locked nucleic acid (LNA) probe.
Although FCH/4 is less virulent than the FVO strain, it was chosen as a one of the two challenge strains because it was the nearest in amino acid sequence of AMA1 to 3D7 among a group of monkey adapted P. falciparum strains available for challenge infections.
HI titers were overall somewhat lower for the clade 1 challenge strain (A/Vietnam/1203/04) than for clade 2 strains.
Therefore, we cannot rule out that priming by the O-PS precursors could contribute to an antibody response to the challenge strain accounting in part for protection.
From all necropsy samples of both challenged and non-challenged pigs, 27, 13 and 41% were found positive for the challenge strain in group A, B and C, respectively, with a significant difference between group B and C (P < 0.01) (Table 2).
