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The ninth ranked challenge, finishing closely behind the challenges associated with research, was the challenge of substitute decision making.
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McBride was dismissed for a late challenge on substitute Chris Lyons.
The former Liverpool player could have few complaints after an ugly challenge on substitute Campbell.
Then came the penalty, awarded for Michael Liddle's challenge on substitute Paris Cowan-Hall.
In the recent years the science of condensation heat transfer has been severely challenged by the adoption of substitute working fluids and new enhanced surfaces for heat exchangers.
We focus on the major technical challenge of DOSNs: they need to substitute the datacenter-based infrastructure of centralized OSNs.
A major challenge of our approach was to substitute the feedback-loop signaling from more mature bone marrow compartments back to stem cells.
In the afternoon the attention turned to crosscutting issues such as the challenges of developing a substitute for a scarce material; the way that information on mineral production and reserves is gathered by the Minerals Information Team of the US Geological Survey; and the way that other countries have responded to potential shortfalls of energy-critical elements.
Moreover, the penal substitution theory faces the challenge of explaining how it could possibly be just to allow a substitute to bear someone else's punishment.
Ethnic nationalism provides a kind of substitute.
Challenges to substituting machines for workers in tasks requiring flexibility, judgment, and common sense remain immense".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com