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To make this technique reproducible, there still exist the challenge of proper calibration and validation of such mechanical assessment.
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The extreme clonal heterogeneity of most tumours is also a challenge for proper evaluation of predictive biomarkers in oncology.
For non-volatile compounds, the variable degree of dilution with water vapor can present a challenge to proper interpretation of EBC concentration data [32], [33]; however, for volatile compounds such as formic acid, EBC concentration is influenced by factors related to volatilization more so than water vapor condensation.
However, this requires isolation of ECs from diseased tissue, which at present poses technical and interpretational challenges for proper analysis of metabolism using advanced metabolomics methods.
They suggest that the FTC is over-enforcing by challenging a lack of proper data security practices as unfair.
Then she faced the challenge of determining a proper design.
But this belies the more basic challenge of creating a proper venture-capital industry.
With the myriad of formalisms that have been applied in SB, we face the challenge of choosing the proper formalism for the problem in hands.
10 However, because of the pronounced radical character, unrestricted DFT methods must be used, 9a which are afflicted with spin contamination problems and the challenge of choosing a proper functional.
RBMK is a water-cooled graphite-moderated channel-type power reactor and the decommissioning of these reactors faces specific challenges for proper characterisation and disposal of irradiated reactor graphite.
Management of municipal solid wastes (MSW) which are produced in metropolitan cities is great challenge in the absence of proper technology for elimination and processing of these biowastes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com