Sentence examples for challenge of altering from inspiring English sources

Instead, he said, it was to tackle the challenge of altering a face according to agreed-upon standards of attractiveness, while producing a result that left the face completely recognizable, rather than the product of cosmetic surgery or digital retouching.

Antimicrobial therapy in obese patients for different infections, including pneumonia, represents a clinical challenge because of altered pharmacokinetics and pharmacodynamics.

Not only is the sheer exercise of aggregating data about thousands of cases arduous but the process of altering an ingrained system with heaps of information is challenging.

"It would require a legal challenge to alter this.

Physiological levels of leptin can modulate the response to an inflammatory challenge by altering production of proinflammatory and anti-inflammatory cytokines and may also affect cytokine signaling by a variety of mechanisms, including induction of SOCS-3 [ 33].

It is considerably challenging to alter the design of existing large and tall buildings to make them rely on natural energy due to many reasons.

Managers often face the challenge of environments already altered by previous actions and subjected to ongoing actions that may substantially change the selective regime.

In its early days the Bank's biggest security challenge was forgers altering the value of a note, for instance from £10 to £20, rather than attempting to replicate the note itself.

The challenge is in altering the ratio of gravity and wit to come up with something genuinely engaging.

The ultimate aim of this module is to identify, challenge and alter dysfunctional attitudes of patients into helpful ones that fit in the current circumstances [ 28].

A bolt of altered perspective.