Sentence examples for challenge observed from inspiring English sources

One challenge observed with the MSM technique is that the fitting process fails when there are insufficient neighbouring sensors within range R q - at least two are required to successfully generate spatial functions for each sensor.

In line with the rapid rise in temperature after challenge observed in the prophylaxis experiment ferrets treated with CR6261 24 hours after challenge showed a mean maximal temperature of 41.5°C before CR6261 was administered (p = 0.15 versus 41.8°C of the control group, figure 2C).

The IL-10 response is thought to reflect the strength of the preceeding inflammatory response [ 35], and the constant low expression of IL-10 might be explained by the relative low bacterial challenge observed in the present study.

This is consistent with the reduction of myofibroblast counts in MR16-1-treated mice, upon bleomycin challenge, observed in our study and previously reported by Kitaba et al. [ 13].

32 In order to address the drug resistance challenge observed in the clinical management of RB, there is an urgent need to identify the responsible genes in order to aid the prognostic stratification.

Firstly, transcriptional regulation of COX-2 and mPGES-1 needs at least 90 min (Cao et al., 2001; Elmquist et al., 1997), and therefore cannot explain the behavioural responses to LPS challenge observed 30 min after administration (Swiergiel and Dunn, 2002).

Allosteric inhibitors, such as IPA-3, leverage the unique Group I PAK autoregulatory domain for selective inhibition, and this approach might provide an outlet to evade the kinase selectivity challenges observed with ATP-competitive PAK inhibitors.

Challenges observed in the process of recruitment and issues that could affect genotype analysis were documented.

The reviewed mechanisms avoid the methodological challenges observed for medicine price comparisons that only use national price databases.

However, we believe that the challenges observed are recognisable also for frail patients in general when focusing on transitional care.

It is also important to note that some of the challenges observed in other studies were institution-specific.