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In this study, challenge models for effluent transmission of classical vibriosis and atypical furunculosis between Atlantic salmon, cod and halibut have been evaluated by the use of a tank system designed for transmission via effluent.
The immune responses were shown to be protective in animal challenge models for a subcutaneous (s.c).
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Raengsakulrach, B. et al. An intranasal challenge model for testing Japanese encephalitis vaccines in rhesus monkeys.
The need for further development of the human challenge model for P. vivax vaccines and specific considerations for conduct of field trials with P. vivax vaccines was outlined.
In this work, we showed that mice deficient in the alpha/beta interferon receptor (IFNAR mice) were highly susceptible to USUV infection and provided a lethal challenge model for vaccine testing.
In 2011, WRAIR and NIH sponsored a workshop to discuss "reintroducing" the human challenge model for dengue.
The second aim was to develop a new challenge model for ETEC, involving an epidemiologically relevant strain.
The objective of this study was to select a dietary challenge model for the assessment of inflammatory resilience.
C3 cell line was already utilized as challenge model for E6/E7 therapeutic vaccines but for E5 therapeutic vaccine no information was available regarding the E5 expression.
A defined animal model for this phase of the infection can help to investigate host-MAP interactions in apparently healthy animals and identify surrogate markers for disease progress and might also serve as challenge model for vaccines.
To increase the capacity to perform Phase IIB trials with human ETEC vaccines, and to introduce a new challenge model for such studies, we undertook an experimental infection study in a hospital ward at Haukeland University Hospital (HUH), Bergen, Norway, with an epidemiologically relevant wild-type ETEC strain previously not used to experimentally infect volunteers.
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CEO of Professional Science Editing for Scientists @ prosciediting.com